{"id":1833,"date":"2024-04-15T15:50:48","date_gmt":"2024-04-15T07:50:48","guid":{"rendered":"https:\/\/nebula-b.com\/?page_id=1833"},"modified":"2025-01-16T16:51:41","modified_gmt":"2025-01-16T08:51:41","slug":"small-animal-in-vivo-imaging","status":"publish","type":"page","link":"http:\/\/nebula-b.com\/de\/in-vivo-bildgebung-bei-kleintieren\/","title":{"rendered":"Multimodales In-vivo-Bildgebungssystem f\u00fcr Kleintiere"},"content":{"rendered":"<div class=\"wp-block-uagb-container uagb-block-a203b57d alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-columns has-small-font-size is-layout-flex wp-container-core-columns-is-layout-b934f1a7 wp-block-columns-is-layout-flex\" style=\"border-style:none;border-width:0px;border-radius:0px;padding-top:0;padding-right:var(--wp--preset--spacing--20);padding-bottom:0;padding-left:var(--wp--preset--spacing--20)\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:40%\">\n<div class=\"wp-block-stackable-carousel stk-block-carousel stk--is-slide stk--arrows-justify-space-between stk--arrows-align-center stk-block stk-fd1a0a7\" data-slides-to-show=\"\" data-block-id=\"fd1a0a7\"><div class=\"stk-block-carousel__content-wrapper\"><div class=\"stk-row stk-inner-blocks stk-block-content stk-block-carousel__slider-wrapper stk-content-align stk-fd1a0a7-column\"><div class=\"stk-block-carousel__slider\" role=\"list\" data-autoplay=\"4000\" data-label-slide-of=\"Slide %%d of %%d\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-dcbaa5d\" data-v=\"4\" data-block-id=\"dcbaa5d\"><style>.stk-dcbaa5d{align-self:center !important}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-dcbaa5d-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-dcbaa5d-inner-blocks\">\n<div class=\"wp-block-stackable-image stk-block-image has-text-align-center stk-block stk-ccdae6d\" data-block-id=\"ccdae6d\"><style>.stk-ccdae6d .stk-img-wrapper{width:91% !important;height:600px !important}<\/style><figure><span class=\"stk-img-wrapper stk-image--shape-stretch\"><img alt=\"Multimodales In-vivo-Bildgebungssystem f\u00fcr Kleintiere\" loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-1879\" src=\"https:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/\u6d3b\u4f53N-removebg-preview-vmake.png\" width=\"329\" height=\"506\" srcset=\"http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/\u6d3b\u4f53N-removebg-preview-vmake.png 329w, http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/\u6d3b\u4f53N-removebg-preview-vmake-195x300.png 195w\" sizes=\"auto, (max-width: 329px) 100vw, 329px\" \/><\/span><\/figure><\/div>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-17ee126\" data-v=\"4\" data-block-id=\"17ee126\"><style>.stk-17ee126{align-self:center !important}.stk-17ee126-inner-blocks{justify-content:space-around !important}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-17ee126-container stk--no-background stk--no-padding\"><div class=\"has-text-align-center stk--column-flex stk-block-content stk-inner-blocks stk-17ee126-inner-blocks\">\n<div class=\"wp-block-stackable-image stk-block-image stk-block stk-2eca6b3\" data-block-id=\"2eca6b3\"><figure><span class=\"stk-img-wrapper stk-image--shape-stretch\"><img alt=\"Multimodales In-vivo-Bildgebungssystem f\u00fcr Kleintiere\" loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-1836\" src=\"https:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/\u5c0f\u52a8\u7269\u6d3b\u4f531.jpg\" width=\"962\" height=\"550\" srcset=\"http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/\u5c0f\u52a8\u7269\u6d3b\u4f531.jpg 962w, http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/\u5c0f\u52a8\u7269\u6d3b\u4f531-300x172.jpg 300w, http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/\u5c0f\u52a8\u7269\u6d3b\u4f531-768x439.jpg 768w\" sizes=\"auto, (max-width: 962px) 100vw, 962px\" \/><\/span><\/figure><\/div>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-38e7709\" data-v=\"4\" data-block-id=\"38e7709\"><style>.stk-38e7709{align-self:center !important}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-38e7709-container stk--no-background stk--no-padding\"><div class=\"has-text-align-center stk-block-content stk-inner-blocks stk-38e7709-inner-blocks\">\n<div class=\"wp-block-stackable-image stk-block-image stk-block stk-f8b336b\" data-block-id=\"f8b336b\"><figure><span class=\"stk-img-wrapper stk-image--shape-stretch\"><img alt=\"Multimodales In-vivo-Bildgebungssystem f\u00fcr Kleintiere\" loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-1835\" 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class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"border-style:none;border-width:0px;flex-basis:60%\">\n<p style=\"font-size:16px\"><strong>Merkmale<\/strong> <\/p>\n\n\n\n<p><strong>\u2727 R\u00fcckseitig beleuchtete, hochempfindliche Kryokamera<\/strong><br>Die Live-Bildgebungssysteme f\u00fcr Kleintiere verwenden hochaufl\u00f6sende kryogene, von hinten beleuchtete Kameras mit einer QE von bis zu 95% in der Spitze und einer K\u00fchltemperatur von -100 \u00b0C. Mit einem F0,95-Objektiv mit gro\u00dfer Blenden\u00f6ffnung sind sowohl das Signal-Rausch-Verh\u00e4ltnis als auch die Empfindlichkeit ausgezeichnet;<br><strong>\u2727 Gleichm\u00e4\u00dfigkeit der Anregungslichtquelle<\/strong><br>Es verf\u00fcgt \u00fcber eine Hochleistungs-Schmalbandr\u00f6hre und eine langlebige LED-Lichtquelle, und mehrere Lichtquellengruppen sind mit einer globalen schattenfreien Symmetrie konzipiert, um eine gleichm\u00e4\u00dfige und stabile Anregungslichtquelle und die Stabilit\u00e4t der Fluoreszenzanregungsergebnisse zu gew\u00e4hrleisten.<br><strong>\u2727 Spektrale Trennungstechnologie<\/strong><br>Angesichts der unterschiedlichen Grade der Autofluoreszenz bei Tieren, die die Versuchsergebnisse beeinflussen, verwenden wir hochreine, hochtransparente Filter mit schmaler Bandbreite in Kombination mit unserer eigenen Software, um eine Reihe pr\u00e4ziser Spektraltrennungstechnologien zu entwickeln, die es den Benutzern erm\u00f6glichen, Zielfluoreszenzdaten pr\u00e4zise zu erhalten.<br><strong>\u2727 Professionelle In-Vivo-Bildgebungssoftware Nebula-IMAGEIVIS<\/strong><br>Gef\u00fchrter Aufnahmemodus. Je nach Modul enth\u00e4lt es eine Datenbank mit h\u00e4ufig verwendeten Fluoreszenzfarbstoffen. Farbstoffe k\u00f6nnen direkt f\u00fcr die automatische Aufnahme ausgew\u00e4hlt werden. Es werden bis zu 5-Kanal-Probenaufnahmen gleichzeitig unterst\u00fctzt. Fluoreszenzbilder und Markierungsbilder werden zusammengef\u00fchrt. Drei Farben werden automatisch zusammengef\u00fchrt. Manuelle Anpassungen nach dem Zusammenf\u00fchren werden unterst\u00fctzt. Die Ergebnisse k\u00f6nnen spektral getrennt und Grauwerte und Photonenmengen automatisch berechnet werden.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p><strong>Anwendung<\/strong><\/p>\n\n\n\n<p>Gentherapie<br>Normale Gene oder Gene mit therapeutischer Wirkung werden auf bestimmte Weise in Zielzellen eingebracht, um Gendefekte zu korrigieren oder therapeutische Wirkungen zu erzielen und so den Zweck der Behandlung von Krankheiten zu erreichen.<\/p>\n\n\n\n<p>Infrarot-Bildgebung<br>Es eignet sich f\u00fcr die ICG- und Infrarot-Photothermie-Farbstoff-W\u00e4chterlymphknotenbildgebung, die Tiefentumorbildgebung und die subkutane Tumorresektion bei M\u00e4usen.<\/p>\n\n\n\n<p><strong>Erweiterte Anwendung<\/strong><\/p>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-27a174b3 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-525705ec\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"344\" height=\"276\" src=\"https:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/1.png\" alt=\"Multimodales In-vivo-Bildgebungssystem f\u00fcr Kleintiere\" class=\"wp-image-1842\" style=\"width:259px;height:auto\" srcset=\"http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/1.png 344w, http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/1-300x241.png 300w\" sizes=\"auto, (max-width: 344px) 100vw, 344px\" \/><\/figure>\n\n\n\n<p>Fluoreszenz-Western-Blot<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-0788e359\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"361\" height=\"262\" src=\"https:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/2.png\" alt=\"Multimodales In-vivo-Bildgebungssystem f\u00fcr Kleintiere\" class=\"wp-image-1843\" style=\"width:277px;height:auto\" srcset=\"http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/2.png 361w, http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/2-300x218.png 300w\" sizes=\"auto, (max-width: 361px) 100vw, 361px\" \/><\/figure>\n\n\n\n<p class=\"has-text-align-center\">Westlicher Fleck<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-aad1534a\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"383\" height=\"264\" src=\"https:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/3.png\" alt=\"Multimodales In-vivo-Bildgebungssystem f\u00fcr Kleintiere\" class=\"wp-image-1844\" style=\"width:281px;height:auto\" srcset=\"http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/3.png 383w, http:\/\/nebula-b.com\/wp-content\/uploads\/2024\/04\/3-300x207.png 300w\" sizes=\"auto, (max-width: 383px) 100vw, 383px\" \/><\/figure>\n\n\n\n<p class=\"has-text-align-center\">In-Cell-Western<\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n<p><strong>Parameter<\/strong><\/p>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<figure class=\"wp-block-table is-style-stripes\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Modell Nr. <\/strong><\/td><td><strong>LASER-6000<\/strong><\/td><td><strong>LASER-9000<\/strong><\/td><td><strong>LASER-9500<\/strong><\/td><\/tr><tr><td><strong>Aufl\u00f6sung<\/strong><\/td><td> 12 Megapixel<\/td><td>6,6 Megapixel<\/td><td>2 Megapixel<\/td><\/tr><tr><td><strong>K\u00fchltemperatur<\/strong><\/td><td>-45\u00b0C <\/td><td>-75\u00b0C <\/td><td>-75\u00b0C <\/td><\/tr><tr><td><strong>Pixel Gr\u00f6\u00dfe<\/strong><\/td><td> 4,63 x 4,63 \u03bcm<\/td><td>7,4 x 7,4 \u03bcm <\/td><td>13*13\u03bcm<\/td><\/tr><tr><td><strong>Lichtempfindlichkeitseffizienz <\/strong><\/td><td>Hohe QE:&gt;95%<\/td><td>Hohe QE:&gt;95%<\/td><td>Hohe QE:&gt;95%<\/td><\/tr><tr><td><strong>Graustufen<\/strong><\/td><td>16 Bit (0-65535)<\/td><td>16 Bit (0-65535)<\/td><td>16 Bit (0-65535)<\/td><\/tr><tr><td><strong>Expositionszeit<\/strong><\/td><td>1 ms ~ 60 Minuten<\/td><td>1 ms ~ 60 Minuten<\/td><td>1 ms ~ 60 Minuten<\/td><\/tr><tr><td><strong>Pixel-Binning<\/strong><\/td><td>1\u00d71, 2\u00d72, 4\u00d74\u20268\u00d78<\/td><td>1\u00d71, 2\u00d72, 4\u00d74\u20268\u00d78 <\/td><td>1\u00d71, 2\u00d72, 4\u00d74\u20268\u00d78<\/td><\/tr><tr><td><strong>Dynamikbereich<\/strong><\/td><td>\u22654.8 Bestellungen<\/td><td>\u22654.8 Bestellungen<\/td><td>\u22654.8 Bestellungen<\/td><\/tr><tr><td><strong>Motorisiertes Objektiv<\/strong><\/td><td>F=0,95\/35MM Autofokus-Objektiv Standard, F0,8-Objektiv optional<\/td><td>F=0,95\/35MM Autofokus-Objektiv Standard, F0,8-Objektiv optional <\/td><td>F=0,95\/35MM Autofokus-Objektiv Standard, F0,8-Objektiv optional<\/td><\/tr><tr><td><strong>RGB-Lichtquelle<\/strong><\/td><td>RGB-Standard, andere optional<\/td><td>RGB-Standard, andere optional<\/td><td>RGB-Standard, andere optional<\/td><\/tr><tr><td><strong>IR-Lichtquelle<\/strong><\/td><td>Duale Infrarot-Lichtquelle als Standard<\/td><td>Duale Infrarot-Lichtquelle als Standard<\/td><td>Duale Infrarot-Lichtquelle als Standard<\/td><\/tr><tr><td><strong>Filterrad<\/strong><\/td><td>7-socket filter wheel standard, <br>others optional<\/td><td>7-socket filter wheel standard, <br>others optional<\/td><td>7-socket filter wheel standard, <br>others optional<\/td><\/tr><tr><td><strong>Filter <\/strong><\/td><td>530nm, 570nm, 610nm, 670nm, 720nm, 820nm standard;<br>530nm~800nm optional<br><\/td><td>530nm, 570nm, 610nm, 670nm, 720nm, 820nm standard;<br>530nm~800nm optional<\/td><td>530nm, 570nm, 610nm, 670nm, 720nm, 820nm standard;<br>530nm~800nm optional<\/td><\/tr><tr><td><strong>Wei\u00dfe Lichtquelle<\/strong><\/td><td>LED Kaltlicht<\/td><td>LED Kaltlicht<\/td><td>LED Kaltlicht<\/td><\/tr><tr><td><strong>Bildgebungsbereich<\/strong><\/td><td>unterst\u00fctzt maximal 5 M\u00e4use zum Schie\u00dfen<\/td><td>unterst\u00fctzt maximal 5 M\u00e4use zum Schie\u00dfen<\/td><td>unterst\u00fctzt maximal 5 M\u00e4use zum Schie\u00dfen<\/td><\/tr><tr><td><strong>Temperaturkontrollplattform<\/strong><\/td><td>26 \u2013 40 \u00b0C \u00b1 1 \u00b0C<\/td><td>26 \u2013 40 \u00b0C \u00b1 1 \u00b0C<\/td><td>26 \u2013 40 \u00b0C \u00b1 1 \u00b0C<\/td><\/tr><tr><td><strong>An\u00e4sthesie-Luftd\u00fcse<\/strong><\/td><td>supports 5 mice maximum <br>for anesthesia<\/td><td>supports 5 mice maximum <br>for anesthesia<\/td><td>supports 5 mice maximum <br>for anesthesia<\/td><\/tr><tr><td><strong>Geplantes Ausschalten<\/strong><\/td><td>5~60 Minuten<\/td><td>5~60 Minuten<\/td><td>5~60 Minuten<\/td><\/tr><tr><td><strong>Narkoseger\u00e4t f\u00fcr Kleintiere<\/strong><\/td><td>Optional<\/td><td>Optional <\/td><td>Optional<\/td><\/tr><tr><td><strong>Type of heating<\/strong><\/td><td>platform heating or air conditioning<\/td><td>platform heating or air conditioning<\/td><td>platform heating or air conditioning<\/td><\/tr><tr><td><\/td><td><\/td><td><\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Features \u2727 Back-illuminated high-sensitivity cryogenic cameraThe small animal live imaging systems use high-resolution cryogenic back-illuminated cameras with a QE of up to 95% at the peak and a cooling temperature of -100\u00b0C. With an F0.95 large aperture lens, the signal-to-noise ratio and sensitivity are both excellent ;\u2727 Uniformity of excitation light sourceIt adopts high-power narrow-band&hellip;&nbsp;<a href=\"http:\/\/nebula-b.com\/de\/in-vivo-bildgebung-bei-kleintieren\/\" class=\"\" rel=\"bookmark\">Weiterlesen \u00bb<span class=\"screen-reader-text\">Multimodales In-vivo-Bildgebungssystem f\u00fcr Kleintiere<\/span><\/a><\/p>","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","ub_ctt_via":"","neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"","neve_meta_content_width":0,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-1833","page","type-page","status-publish","hentry"],"featured_image_src":null,"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"trp-custom-language-flag":false,"neve-blog":false},"uagb_author_info":{"display_name":"liu, stacey","author_link":"http:\/\/nebula-b.com\/de\/author\/stacey\/"},"uagb_comment_info":0,"uagb_excerpt":"Features \u2727 Back-illuminated high-sensitivity cryogenic cameraThe small animal live imaging systems use high-resolution cryogenic back-illuminated cameras with a QE of up to 95% at the peak and a cooling temperature of -100\u00b0C. With an F0.95 large aperture lens, the signal-to-noise ratio and sensitivity are both excellent ;\u2727 Uniformity of excitation light sourceIt adopts high-power narrow-band&hellip;&nbsp;Weiterlesen&hellip;","_links":{"self":[{"href":"http:\/\/nebula-b.com\/de\/wp-json\/wp\/v2\/pages\/1833","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/nebula-b.com\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/nebula-b.com\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/nebula-b.com\/de\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/nebula-b.com\/de\/wp-json\/wp\/v2\/comments?post=1833"}],"version-history":[{"count":1,"href":"http:\/\/nebula-b.com\/de\/wp-json\/wp\/v2\/pages\/1833\/revisions"}],"predecessor-version":[{"id":2411,"href":"http:\/\/nebula-b.com\/de\/wp-json\/wp\/v2\/pages\/1833\/revisions\/2411"}],"wp:attachment":[{"href":"http:\/\/nebula-b.com\/de\/wp-json\/wp\/v2\/media?parent=1833"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}